U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 821 - 830 of 1033 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

PNU-177864 is a selective antagonist of D3 receptor. Compound was considered as a drug candidate for the chronic treatment of schizophrenia, but severe myopathy was found in skeletal muscles of rats during the initial safety evaluation of PNU-177864. Myopathy was associated with phospholipidosis in numerous tissues.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Nitracaine, a new psychoactive substance, a structural analog of the dopamine reuptake inhibitor, dimethocaine; intended for research applications. The physiological and toxicological properties of this compound are still not known.