Taraxasteryl acetate was identified as the major triterpenoid of the root bark of Scolymus hispanicus L. Antispasmodic. Taraxasterol acetate exhibits antiinflammatory activity. In mice ear edema (induced by phorbol-12-mirystate-13-acetate, croton oil, and arachidonic acid), taraxasteryl acetate showed a topical anti-inflammatory activity. Furthermore, it was found that taraxasteryl acetate has potent preventive activity against acute hepatic failure induced by P. acnes and LPS in a dose-dependent manner. There are also reports of a secondary effect of taraxasteryl acetate on the heat shock protein response.

β-Estradiol 17-acetate is a natural metabolite of estradiol. Hydrolytic enzymes in human cadaver, hairless dog, rat and hairless mouse skin can metabolize β-Estradiol 17-acetate to β-Estradiol. β-Estradiol 17-acetate transported across the human and hairless dog skin can be effectively metabolized before entering the capillary.