U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 791 - 800 of 21518 results

Status:
Investigational
Source:
NCT04586335: Phase 1 Interventional Terminated Ovarian Cancer
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT03748199: Phase 1/Phase 2 Interventional Completed Cystic Fibrosis
(2018)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00951743: Phase 2 Interventional Unknown status HIV Infections
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


DAPTA (D-ala-peptide T-amide) is a synthetic peptide that prevents HIV entry by blocking binding of HIV gp120 protein with CCR5 receptor. In a small clinical study of internasal formulation of DAPTA in long-term infected HIV patients, administration of DAPTA led to decrease in the amount of virus isolated from white blood cells, an increase in gamma-interferon secreting T-cells in the absense of drug-related toxicity. In another clinical study DAPTA in combination with antiretroviral therapy reduced the peripheral (plasma and serum) viral load, but did not reduce the CSF viral load.
Status:
Investigational
Source:
Psychopharmacol Bull. 1991;27(3):237-45.: Phase 2 Human clinical trial Completed Acquired Immunodeficiency Syndrome/psychology
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT02837900: Phase 2 Interventional Completed Knee Osteoarthritis
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00278980: Phase 2 Interventional Completed Diabetes Mellitus, Type 1
(2003)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT01861873: Phase 2 Interventional Unknown status Liver Metastases
(2013)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT02041221: Phase 1/Phase 2 Interventional Completed Asthma
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT01070238: Phase 1/Phase 2 Interventional Completed Type 2 Diabetes
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:sabizabulin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)