Search results for "Pharmacologic Substance[C1909]|Hormone Therapy Agent[C147908]|Hormone Antagonist[C547]" in comments (approximate match)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Epostane (WIN-32729) a pure competitive inhibitor of 3-beta-hydroxysteroid dehydrogenase. Epostane blocks progesterone synthesis during the luteal phase and in pregnancy in women and has strong anti-steroidogenic effect in endocrine tissues. Epostane...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Abarelix is a synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist t...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Trilostane is a synthetic steroid, which interferes with the formation of both cortisol and aldosterone. It is an inhibitor of 3 beta-hydroxysteroid dehydrogenase. This drug under trade name MODRASTANE was withdrawn from human use in the United Stat...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Aminoglutethimide, marketing as Cytadren has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. Cytadren is indicated for the suppression of adrenal function in selected pat...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
IOTHIOURACIL, in a form of sodium salt, was used as an antithyroid agent in the treatment of hyperthyroidism. It is selectively incorporated into the melanin pigment of melanomas during biosynthesis by serving as false melanin precursors. Radiolabell...
Quadrosilan is is a synthetic nonsteroidal estrogen that was developed in the 1970s and that is or has been used as an antigonadotropic agent in the treatment of prostate cancer. It is an organosilicon compound and is also known as 2,6-cisdiphenylhex...
Amadione is a steroidal progestogenic antiandrogen. Its anti-androgenic properties were confirmed by blockade of androgen-induced increase in seminal acid phosphatase content.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Atosiban (brand name Tractocile) is a competitive antagonist of human oxytocin at receptor level. In rats and guinea pigs, atosiban was shown to bind to oxytocin receptors, to decrease the frequency of contractions and
the tone of the uterine muscula...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Cyproterone belongs to a group of medications known as steroidal antiandrogens. It suppresses testosterone and its metabolites. It has approximately three-fold lower potency as an antagonist of the androgen receptor relative to cyproterone acetate. C...