U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 51 - 60 of 95 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

D&C BLUE NO. 9, a color additive, which is used for coloring cotton and silk surgical sutures.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
US Previously Marketed
Source:
DIRECT SKY BLUE by WYETH
(1953)
Source URL:
First approved in 1953
Source:
DIRECT SKY BLUE by WYETH
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
First approved in 2021

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
Source:
Canada:INDIGO
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Indigo, or indigotin, is a dyestuff originally extracted from the varieties of the indigo and woad plants. Indigo was known throughout the ancient world for its ability to color fabrics a deep blue. Egyptian artifacts suggest that indigo was employed as early as 1600 B.C. and it has been found in Africa, India, Indonesia, and China. Indigo is unique in its ability to impart surface color while only partially penetrating fibers. When yarn died with indigo is untwisted, it can be seen that the inner layers remain uncolored. The dye also fades to give a characteristic wom look and for this reason it is commonly used to color denim.
Status:
Possibly Marketed Outside US
Source:
Spray for Children SPF 50+ by Pierre Fabre Dermo Cosmetique Usa, Inc. [Canada]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Bisoctrizole (Tinosorb M) is a hybrid type sun blocking agent acting as both chemical and physical sunscreen. Bisoctrizole is a hybrid UV absorber, the only organic UV filter produced and microfine organic particles (< 200 nm), like microfine zinc oxide and titanium dioxide. Where other organic UV absorbers need to be dissolved in either the oil or water phase, bisoctrizole dissolves poorly in both. It covers both UVA and UVB range. Furthermore, it does not degrade under sunlight and is not significantly absorbed into the skin. It appear highly compatible with many other common sun blocking agents. Overall, it appears to have a good safety profile, even though current safety data are insufficient and long-term human safety studies are lacking. Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro. Bisoctrizole is not approved by the U.S. Food and Drug Administration (FDA), but is approved in the EU and other parts of the world. Bisoctrizole is highly stable and also has a stabilizing effect on other UV absorbers, particularly the UVB blocker octyl methoxycinnamate (octinoxate). Bisoctrizole appears to be relatively non-toxic and rarely causes skin irritation. As with many synthetic chemicals, it is unclear whether bisoctrizole may produce low-level skin damage or systemic effects with long-term use. Considering that bisoctrizole is stable, poorly soluble and minimally absorbed by the skin, the risks appear to be low. Still, more research is on bisoctrizole safety is needed.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Medronic acid (conjugate base, medronate) is a diagnostic agent that is used in complex with technetium Tc-99m for imaging delineate areas of altered osteogenesis. Upon administration the complex binds to hydroxyapatite crystals in bone.