Corosolic acid is a pentacyclic triterpene acid isolated from Lagerstroemia speciosa. It inhibits STAT3 and VEGFR2 signaling and has cytotoxic effect on a number of tumor cell lines. Corosolic acid has demonstrated anti-diabetic effect in vivo, probably due to facilitation of GLUT4 translocation or AMPK activation.

Ceanothic acid, a substance previously isolated by Julian, Pikl, and Dawson, has been shown to be a triterpenoid related to the lupeol–betulin group, but in which ring A is five-membered. It has been degraded to the keto ester A norbetulonic acid methyl ester, a substance of defined constitution and stereochemistry. A recent study revealed that Paliurus ramossisimus (Rhamnaceae) is rich in ceanothic acid. Ceanothic Acid shows potent cytotoxicity on OVCAR-3, HeLa, and FS-5 Cells