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473
Possibly Marketed Outside US
13
Investigational
3
US Approved Rx
2
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Primary Target
Muscarinic acetylcholine receptor M1
3
AGS
2
Colon carcinoma cells
2
PC-3
2
Thymidylate synthase
2
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Highest Phase
Approved
5
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Approval Year
Unknown
480
1962
2
2009
2
2013
2
1982
1
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Condition
Unknown
7
Cutaneous leishmaniasis
3
Adenocarcinoma of the colon
2
Breast adenocarcinoma
2
Breast cancer
2
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Treatment Modality
Curative
4
Primary
3
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CNS Activity
CNS Penetrant
3
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Originator
Roche
2
Roszowski, A.P.
2
AstraZeneca
1
Deville, S.C.
1
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Substance Class
Chemical
454
Protein
22
Polymer
10
Structurally Diverse
2
Concept
1
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INN Stem
Chemical substance(-ine)
3
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Code System
FDA UNII
489
CAS
451
PUBCHEM
448
EPA CompTox
375
ECHA (EC/EINECS)
213
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Protein Type
PEPTIDE
5
CYTOKINE
1
ENZYME
1
PREPROTEIN
1
STRUCTURAL PROTEIN
1
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
1
DERMATOLOGICALS
1
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ATC Level 2
ANTIFUNGALS FOR DERMATOLOGICAL USE
1
ANTINEOPLASTIC AGENTS
1
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ATC Level 3
ANTIFUNGALS FOR TOPICAL USE
1
ANTIMETABOLITES
1
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ATC Level 4
Other antifungals for topical use
1
Pyrimidine analogues
1
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Substance Form
Principal Form
462
Salts, Hydrates, Esters, etc.
27
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Sodium 4-amino-m-xylene-5-sulfonate
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567637QW7R
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
2-(4-Amino-N-ethyl-m-toluidino)ethanol nitrate
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69AC58L65A
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
M-DIMETHYLAMINOMETHYLENEIMINOPHENOL HYDROCHLORIDE
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93UOG6A864
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
4,.ALPHA.-DIMETHYL-M-TYRAMINE HYDROCHLORIDE
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QX58THR9Y8
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Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
M-HYDROXYBENZYLPIPERAZINE DIHYDROCHLORIDE
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Z894L0N675
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
M-62812
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89MSZ2934C
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Toll-like receptor 4
6
M-58996
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43AAU6J9GZ
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
M-58373
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JZ5PU2D4AZ
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
5-(M-(ALLYLOXY)PHENYL)-3-(O-ETHYLPHENYL)-S-TRIAZOLE, MONOHYDROCHLORIDE
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28036BO0AS
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
SODIUM M-TOLUENESULFONATE
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AI4D3787YW
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
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