U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 411 - 420 of 12521 results

Status:
Investigational
Source:
NCT03873883: Phase 1 Interventional Completed Solid Tumor, Adult
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT03065010: Phase 1 Interventional Completed Breast Cancer
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Senexin B is a selective CDK8/CDK19 inhibitor developed by Senex Biotechnology Inc. Senexin B is an ATP pocket binder, with very high target selectivity as indicated by kinome profiling. CDK8/19 inhibition produces chemopotentiating, chemopreventive and anti-metastatic effects in different types of cancer.
Status:
Investigational
Source:
INN:bosmolisib [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT03254368: Phase 2 Interventional Completed Type 2 Diabetes Mellitus
(2017)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT04660812: Phase 1/Phase 2 Interventional Active, not recruiting Metastatic Colorectal Cancer
(2021)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT01785147: Phase 2 Interventional Completed Tobacco Addiction
(2013)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT03512171: Phase 1 Interventional Completed Healthy Adults
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT04221230: Phase 2 Interventional Completed Major Depressive Disorder
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT03911310: Phase 3 Interventional Completed Prostate Cancer
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT04435431: Phase 2 Interventional Completed Parkinson Disease
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)