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Restrict the search for
m nalidixic acid
to a specific field?
Status:
US Previously Marketed
Source:
SPARTASE POTASSIUM ASPARTATE by WYETH
(1961)
Source URL:
First marketed in 1921
Class (Stereo):
CHEMICAL (ABSOLUTE)
Disodium aspartate is used in organic biosynthesis.
Status:
US Previously Marketed
First marketed in 1912
Class (Stereo):
CHEMICAL (ACHIRAL)
Neoarsphenamine and related compounds are sulfhydryl-binding agents which are tolerated by man. A large experience in the employment of this drug and its toxic manifestations exists as a result of its former use as an antisyphilitic agent. Tertiary syphilis was a common cause for mental health conditions. Also known as Neosalvarsan, it superseded Salvarsan due to its lower toxicity. Both arsenicals still carried significant risk of side-effects and were themselves replaced by penicillin in the 1940s. Neoarsphenamine was also used for the treatment of amebic dysentery.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
Source:
Phenylcinchoninic Acid U.S.P.
(1921)
Source URL:
First marketed in 1908
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinchophen, phenylcinchoninic acid, seems to have been discovered in 1887 by Doebner and Gieseke and to have been introduced into medicine under the trade name of atophan in 1908 by Nicolaier and Dohrn. Since that time it has been used extensively for gout as well as for other forms of arthritis and for the relief of pain of all types. Use of Cinchophen in humans ceased in the 1930s due to the discovery that it can cause serious liver damage.
Status:
US Previously Marketed
First marketed in 1907
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Tricaine (MS-222, Tricaine-S), a water-soluble local anesthetic, is used commonly for sedation, immobilization, and anesthesia of poikilothermic animals and has been accepted as a common anesthetic for use in the cold-blooded animals. It has long been recognized as a valuable tool for the proper handling of these animals during manual spawning (fish stripping), weighing, measuring, marking, surgical operations, transport, photography, and research. Tricaine was developed by Merck as a sulfonated analog of benzocaine with high solubility in water. The main advantage of Tricaine is the short duration of action and rapid metabolism. There are many reports describing the use of Tricaine for anesthetizing poikilothermic animals because it is a safe agent for immersion anesthesia even though the other anesthetics such as ether, ethanol, thiopental, halothane, isoflurane, barbiturates also could be used. Amphibians could be anesthetized easily by immersion methods with Tricaine because the amphibian skin is extremely permeable and water is absorbed through the skin rather than ingested. Tricaine has been administered as an injectable agent also.
