U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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mixture
Status:
US Previously Marketed
First approved in 1953

Class:
MIXTURE

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). It works by decreasing the production of certain hormones, which reduces testosterone levels in the body. Animal studies comparing triptorelin to native GnRH found that triptorelin had 13 fold higher releasing activity for luteinizing hormone, and 21-fold higher releasing activity for follicle-stimulating hormone. Triptorelin is indicated for the palliative treatment of advanced prostate cancer.