U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 381 - 390 of 5636 results

Status:
Investigational
Source:
NCT03861143: Phase 2 Interventional Completed Ulcerative Colitis
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04231968: Phase 3 Interventional Completed Respiratory Syncytial Virus Infections
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT03770988: Phase 2 Interventional Unknown status Inoperable or Recurrent or Metastatic Esophageal Squamous Carcinoma
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Poziotinib is an inhibitor of EGFR tyrosine kinase family. The drug is being tested in phase II of clinical trials for different cancers: breast cancer, lung adenocarcinoma, head and neck squamous cell carcinoma, HER-2 positive advanced gastric cancer (in combination with Paclitaxel and Trastuzumab).
Status:
Investigational
Source:
INN:enavogliflozin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT04362644: Phase 1 Interventional Recruiting Idiopathic Pulmonary Fibrosis
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

BAY85-8102 (widely known as (18)F-DPA-714) is a specific radioligand for the translocator protein (TSPO). TSPO, formerly known as the peripheral benzodiazepine receptor, is dramatically upregulated under pathologic conditions. BAY85-8102 in combination with positron emission tomography imaging participated in phase I clinical trials for investigation of neuroinflammation in Alzheimer's patients. However, this study was terminated early. Clinical pharmacology/efficacy parameters planned in the protocol were not evaluated at the end of the study
Status:
Investigational
Source:
INN:nuzefatide pevedotin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT04296370: Phase 3 Interventional Recruiting Treatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:nerandomilast [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:foselutoclax [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT02845271: Phase 2 Interventional Completed Osteoarthritis
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)