U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 361 - 370 of 1216 results

Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

The novel compound ICA-069673 was developed by Icagen, Inc. in a screening program to identify subtype-selective KV7 channel activators. It was found, that this compound is a selective KV7.2/KV7.3 (KCNQ2/3) channel opener, which possesses 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. ICA-06967 was orally active in animal models and was used for epilepsy.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)