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Restrict the search for
monomethyl fumarate
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Thenoyltrifluoroacetone (TTFA) is a chelating agent and inhibitor of cellular respiration.
Studies indicate that thenoyltrifluoroacetone is a potent inhibitor of carboxylesterase activity, in addition to its ability to inhibit mitochondrial complex II activity. Thenoyltrifluoroacetone has been shown to specifically inhibit electron transfer from Fe-S centre S-3 (cluster 3) of succinate dehydrogenase to oxidized
ubiquinone and ubisemiquinone pairs.
