U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 321 - 330 of 609 results

Status:
US Previously Marketed
Source:
Foralamin by Eaton
(1950)
Source URL:
First approved in 1950
Source:
Foralamin by Eaton
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
US Previously Marketed
Source:
SEMIKON HCL by BEECHAM LABS
(1961)
Source URL:
First approved in 1947
Source:
Thenylene HCl by Abbott
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Methapyrilene is an antihistamine and anticholinergic of the pyridine chemical class which was developed in the early 1950s. It was sold under the trade names Co-Pyronil and Histadyl EC. It has relatively strong sedative effects, to the extent that its primary use was as a medication for insomnia rather than for its antihistamine action. Together with scopolamine, it was the main ingredient in Sominex, Nytol, and Sleep-Eze. It also provided the sedative component of Excedrin PM. Manufacturers voluntarily withdrew methapyrilineb drug products from the market in May and June 1979, when methapyrilene was demonstrated to cause liver cancer in rats when given chronically.
Status:
US Previously Marketed
Source:
Monomestrol by Wallace & Tiernan
(1943)
Source URL:
First approved in 1943
Source:
Monomestrol by Wallace & Tiernan
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Guaiacol is a naturally occurring organic compound first isolated by Otto Unverdorben in 1826. Although it is biosynthesized by a variety of organisms, this yellowish aromatic oil is usually derived from guaiacum or wood creosote. Guaiacol is used as a reducing co-substrate for COX reactions. It is mainly used as expectorant, antiseptic. It is used as cough suppressant, it is an ingredient of Pulmo Bailly (UK). Pulmo Bailly Cough Expectorant is indicated for relief for cough symptoms that are associated with a flu, cold, or other infection. It contains active ingredients, Codeine and Guajacol, which reduce discomfort and the urge to cough. Each 5 ml tablespoon of Pulmo Bailly contains 75 mg guaiacol and 7 mg codeine.
Status:
Possibly Marketed Outside US
Source:
Sodium Fluoride and Potassium Nitrate by Westminster Pharmaceuticals, LLC
(2022)
Source URL:
First approved in 2022
Source:
Sodium Fluoride and Potassium Nitrate by Westminster Pharmaceuticals, LLC
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lubabegron was initially studied in the Eli Lilly’s lab for potential applications in human health. The drug is a beta-adrenergic agonist that has the effect of increasing the breakdown of fats and increasing energy expenditure in cells. Lubabegron is the first animal drug that was approved to reduce ammonia gas emissions from an animal or its waste. These ammonia gasses can come from many sources and can affect the health of people, animals and the environment.

Showing 321 - 330 of 609 results