U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 311 - 320 of 19755 results

Status:
Investigational
Source:
NCT01028053: Phase 3 Interventional Completed Mild Cognitive Impairment
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN:ISOMYLAMINE HYDROCHLORIDE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

ISOMYLAMINE is a spasmolytic and smooth muscle relaxant.
Status:
Investigational
Source:
NCT02507284: Phase 2 Interventional Completed Irritable Mood
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:doxacurium chloride
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
NCT01107236: Phase 2 Interventional Completed Healthy
(2010)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:toliodium chloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Toliodium is a surfactant used as an antibacterial and antiseptic agent. Also, it was used as an animal food additive.
Status:
Investigational
Source:
INN:tipetropium bromide
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Tipetropium is atropine derivative. It is the adrenoceptor agonist. Tipetropium is bronchospasmolytic agent. It was used as anti-asthmatic drug.
Status:
Investigational
Source:
INN:ditercalinium chloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ditercalinium is the antineoplastic agent. Ditercalinium itself is not a natural product, however, it is derived from the natural product 5,11-dimethyl-6H-pyrido-[4,3- b]carbazole (ellipticine) that was isolated in 1959. It is a rare example of a noncovalent DNA-binding ligand that forms bisintercalation complexes via the major groove of the double helix. Ditercalinium selectively recognizes certain GC-rich sequences in DNA. It preferentialy binds with antiparallel quadruplex sequence d(AG(3)[T(2)AG(3)](3)). Ditercalinium chloride can deplete mitochondrial DNA in both mouse and human cells. Ditercalinium chloride inhibits human DNA polymerase gamma activity as efficiently as does ethidium bromide. Ethidium bromide distributes diffusely in the mitochondria of HeLa cells, while ditercalinium chloride distributes granularly and hence may be strongly associated with mitochondrial DNA.
Status:
Investigational
Source:
INN:laurcetium bromide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT00362024: Phase 2 Interventional Terminated Alzheimer's Disease
(2006)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)