U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 31051 - 31060 of 34953 results

Status:
Designated
Source:
FDA ORPHAN DRUG:731720
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
EU-Orphan Drug:EU/3/04/218
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Designated
Source:
FDA ORPHAN DRUG:515216
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
FDA ORPHAN DRUG:326110
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Calcium benzoate is the calcium salt of benzoic acid. Used as a preservative, both antibacterial and antifungal. Calcium benzoate can be found in concentrated pineapple juice. People who suffer from asthma, aspirin sensitivity or the skin disease urticaria may have allergic reactions and/or find their symptoms become worse following consumption of benzoic acid, particularly in combination with tartrazine (E102). Calcium benzoate (E213) is approved for use as a food additive in the EU, USA and Australia and New Zealand.
Status:
Designated
Source:
FDA ORPHAN DRUG:823621
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium arsenite is an inoganic sodium salt with formula with formula NaAsO2. It has a role as an insecticide, an antibacterial agent, a herbicide, a rodenticide, a carcinogenic agent, an antineoplastic agent and an antifungal agent. It is an arsenic molecular entity and an inorganic sodium salt. Sodium arsenite demonstrated in vitro scolicidal effect against E. granulosus protoscoleces. Sodium arsenite is known to suppress both the IKK-NF-kappaB and JAK2-STAT3 signaling pathways and to activate the MAPK/JNK-cJun pathways, thereby committing some cancers to undergo apoptosis. Sodium arsenite is an effective drug for the treatment of acute promyelocytic leukemia with little nonspecific toxicity. Sodium metaarsenite (KML-001) displaces hTERT from the nucleus and is synergistic with cisplatin. It was used in the clinical trials for the treatment of advanced solid tumors.
Status:
Designated
Source:
FDA ORPHAN DRUG:18787
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Benzylpenilloic acid is a metabolite of benzylpenicillin. It is produced by hydrolysis of when beta-lactam ring of benzylpenicillin. Along with some other metabolites of penicillin, benzylpenilloic acid is responsible for the allergic reaction to beta-lactam antibiotic. It is a component of a minor determinant mixture (MDM) reagent which is used to evaluate sensitivity to penicillin in the clinic.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Showing 31051 - 31060 of 34953 results