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Restrict the search for
testosterone cypionate
to a specific field?
Status:
Investigational
Source:
NCT01809691: Phase 3 Interventional Active, not recruiting Prostate Cancer
(2013)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Orteronel (TAK-700) is a non-steroidal antiandrogen, discovered by Takeda Pharmaceutical Company Limited, that selectively inhibits the 17,20 lyase enzyme (CYP17A1). This enzyme, which is present in both the testes and adrenal glands, is central to the production of steroidal androgens. Synthesis of androgens outside the testes contributes to disease progression in castration-resistant prostate cancer (CRPC). In phase III of clinical trials for metastatic, hormone-refractory prostate cancer it wasn’t shown overall survival rates, and development was voluntarily terminated as a result.
Status:
Investigational
Source:
Eur J Heart Fail. Oct 2022;24(10):1967-1977.: Phase 2 Human clinical trial Completed Shock, Cardiogenic/etiology
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Etiocholanone is an androstane neurosteroid. Etiocholanone potentiates GABA-A receptor currents and exerts anticolvunsant properties in rodents. Etiocholanolone demostrates pyrogenic properties.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Testosterone glucoside is a conjugated form of steroid testosterone investigated at Strakan Ltd (now Kyowa Hakko Kirin Co. Ltd). Testosterone glucoside is bioavailable when given orally, as well as intramuscularly, and is readily metabolised to testosterone. It had been in Phase II study for the treatment of hypogonadism, however development was discontinued.
