U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 21 - 30 of 65 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (RACEMIC)

Mofebutazone (or monophenylbutazone) is a 3,5-pyrazolinedione derivative study for treating asthma and muscular pain. It was found that there was no increase in the incidence or severity of the asthmatic attacks during the course of mofebutazone treatment. The drug tended to improve the tested pulmonary ventilatory functions or at least to leave them unchanged. All the mofebutazone-treated individuals showed a dramatic reduction in the concentrations of PGE2, PGF2alpha, and LTs in their BAL, but there was no consistent correlation between the extent of reduction and the degree of benefit or worsening sustained by an individual patient. Mofebutazone was found to be excreted almost exclusively via the kidney
mixture
Status:
Investigational
Source:
NCT03014596: Not Applicable Interventional Completed Behavioural, Emotional, and Psychosocial Problems
(2017)
Source URL:

Class:
MIXTURE

mixture
Status:
Other

Class:
MIXTURE

mixture
Status:
Other

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
CENASERT IMPROVED METHYLBENZETHONIUM CHLORIDE by CENTRAL PHARCA
(1961)
Source URL:
First approved in 1947
Source:
Diaparene Chloride by Homemaker's (Breon)
Source URL:

Class:
MIXTURE