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Showing 21 - 23 of 23 results

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CYTOCHROME P450 3A4

PUO0521HZV

Subunit 1 (502) Similarity Search

Sequence Search

Subunit 1 (502) Similarity Search

Status:

Other

Class:

PROTEIN

LOPERAMIDE OXIDE MONOHYDRATE, CIS-

NK7EM6QHI9

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

LOPERAMIDE OXIDE MONOHYDRATE

H3VOT77DE1

Search for Structure

Status:

Possibly Marketed Outside US

Source:

WHO-ATC:A07DA05

Source URL:

https://ginas.ncats.nih.gov/ginas/app/substance/NG66S4H2RL

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

oxidation-reduction process

Loperamide Oxide is a prodrug of loperamide, an antidiarrheal agent, patented by Belgian pharmaceutical company Janssen Pharmaceutica N. V. as an antidiarrheal agent. Loperamide oxide is reduced to loperamide and has the same antisecretory potency as loperamide in jejunum and colon. In clinical trials, Loperamide oxide provides a safe and effective treatment for chronic diarrhea associated with Crohn's disease. Loperamide Oxide is used in the Netherlands for the treatment of acute diarrhea in adults under brand name Arestal.

Protein

CYTOCHROME P450 3A4

Structure of LOPERAMIDE OXIDE MONOHYDRATE, CIS-

ACHIRAL

LOPERAMIDE OXIDE MONOHYDRATE, CIS-

Structure of LOPERAMIDE OXIDE MONOHYDRATE

ACHIRAL

LOPERAMIDE OXIDE MONOHYDRATE

Showing 21 - 23 of 23 results

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