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Restrict the search for
hydrocortisone probutate
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Cortisol is metabolized to form 6β-hydroxycortisol (6β-OHF) catalyzed by CYP3A. The metabolite is then excreted in the urine. Therefore, the urinary excretion ratio 6β-OHF/cortisol has extensively been used as a non-invasive index for evaluating the in vivo CYP3A activity in humans. Measurement of urinary 6β-hydroxycortisol is suggested as a good diagnostic test for hypercortisolemic states.
