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Restrict the search for
m aspirin
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
4-(M-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium (McN-A-343) is a selective muscarinic M1 receptors agonist, which leads to its widespread use as an aid to distinguish responses mediated through M₁ receptors from those utilizing M₂ or M₃ muscarinic receptor subtypes, especially in the CNS. McN-A-343 has a number of non-muscarinic actions. These include activation of some types of nicotinic acetylcholine receptors, antagonism of serotonin 5-HT₃ and 5-HT₄ receptor subtypes, inhibition of the uptake mechanism and a local anesthetic action.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Ethyl β-carboline-3-carboxylate or beta-carboline-3-carboxylic acid ethyl ester, an endogenous compound that was isolated from human urine. It is a partial inverse agonist at the benzodiazepine site on the GABA-A receptor. Experiments on rats have shown that ethyl β-carboline-3-carboxylate produces the anxiogenic-like effect but do not affect brainstem activated hippocampal theta.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
9β,10α,17α-pregna-4,6-diene-3,20-dione ((8S,9R,10S,13S,14S,17R)-17-Acetyl-10,13-dimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one) is an isomer of Dydrogesterone, a synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function. 9β,10α,17α-pregna-4,6-diene-3,20-dione is one of major impurities of dydrogesterone. The physiological and toxicological properties of this compound have not been evaluated in humans.
