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Restrict the search for
amphotericin b
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Bay 65-1942 free base (Bay 65-1942) is a selective inhibitor of IKKβ with IC50 value of 10 uM and Ki value of 2 nM. Bay 65-1942 has been reported to provide cardioprotection through specific suppression of NF-κB signaling. It also afforded potent neuroprotection against LPS-induced neurodegeneration through selective inhibition of NF-kappaB activation and may be of potential benefit in the treatment of PD.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
SIRTUIN MODULATOR 1 is a sirtuin modulator developed by Sirtris Pharmaceuticals, Inc. for treating insulin resistance and metabolic syndrome.
![Structure of 1-(1-Methyl-5-nitronaphtho[2,1-b]furan-2-yl)ethanone](/img/3198d8ca-089a-4c33-a98b-7d684834dbbc.svg?size=200&context=udjsqbdhzi)
