U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 201 - 210 of 433 results

Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.548
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Silver phosphate or silver orthophosphate is a chemical compound consists of silver and phosphate. Silver phosphate has different applications, in photocatalysis to remove the antibiotic from water, in silver staining of biological materials, in photography.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (MIXED)



Valnoctamide is a valproic acid derivative associated with a decreased risk for congenital abnormalities and developed by Beersheva Mental Health Center for treatment mania. Valnoctamide has been marketed as an anxiolytic and sedative in several European countries (as Nirvanil), including Italy, Holland, and Switzerland, until the year 2000 but was not actively promoted as an anticonvulsant. It was marketed in the U.S. as Axiquel by McNeil Laboratories in the 1970s. In mice, valnoctamide has been shown to be distinctly less teratogenic than valproic acid. Injection of 3 mkmol ⁄ kg at day 8 of gestation produced only 1% exencephaly (as compared to 0–1% in control mice and 53% in valproate-treated mice). Embryolethality rates showed similar results: 52% with valproate versus 5% in the controls and 2% with valnoctamide. Valnoctamide's patent is expired, and it is not the property of any major pharmaceutical company. Valnoctamide has potential as a therapy in epilepsy including status epilepticus (SE) and neuropathic pain and is currently being developed for the treatment of mania and Schizoaffective Disorder. In clinical trials, Valnoctamide was well tolerated but lacked efficacy in the treatment of symptoms in patients with acute mania.
Status:

Class (Stereo):
CHEMICAL (RACEMIC)

CLOMACRAN, a non-phenothiazine tricyclic compound, is an antipsychotic drug.
mixture
Status:
Other

Class:
MIXTURE

Showing 201 - 210 of 433 results