U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 201 - 210 of 2457 results

Status:
Investigational
Source:
INN:cefaparole
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cefaparole (cephaparole) is a cephem antibiotic of the cephalosporin subclass that was never marketed and used as phmarceutical intermediates for other drugs.
Status:
Investigational
Source:
INN:gloximonam
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Gloximonam (SQ-82531) is a beta-lactam antibiotic. This is a class of antibiotics that contains a beta-lactam ring in their molecular structure, such as penicillin derivatives. Gloximonam is orally absorbed and has shown anti-bacterial activity against different bacteria of the Enterobacteriaceae and Haemophilus influenzae families. Gloximonam is not effective against staphylococci and strict anaerobes (like aztreonam) and (unlike aztreonam) against Pseudomonas aeruginosa.
Status:
Investigational
Source:
INN:tifencillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Thiphencillin is a penicillin analog patented by Abbott Laboratories as an antibacterial agent. Thiphencillin shows potent antibacterial activity against various species and genera of pathogenic bacteria.
Acetic anhydride is an esterification agent for use in prepn. of modified food starch and for acetylation of monoglycerides. Acetic anhydride is a versatile reagent for acetylations, the introduction of acetyl groups to organic substrates. Acetic anhydride is the chemical compound with the formula (CH3CO)2O (commonly abbreviated Ac2O). Ac2O is mainly used for acetylations leading to commercially significant materials. Its largest application is for the conversion of cellulose to cellulose acetate, which is a component of photographic film and other coated materials. Similarly it is used in the production of aspirin, acetyl salicylic acid, which is prepared by the acetylation of salicylic acid. It is also used as a wood preservative via autoclave impregnation to make a longer lasting timber. Ac2O is also used in many industrial processes for the production of plastics, textiles, dyes, photochemical agents, perfumes, explosives and cigarette filters. Because of its use for the synthesis of heroin by the diacetylation of morphine, acetic anhydride (known as 'AA' in clandestine chemistry circles) is listed as a U.S. DEA List II Precursor, and restricted in many other countries.
Status:
Designated
Source:
FDA ORPHAN DRUG:723619
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
FDA ORPHAN DRUG:800720
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
EU-Orphan Drug:EU/3/16/1654
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
FDA ORPHAN DRUG:498415
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)