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National Institutes of Health
NCATS
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Development Status
Other
1,153
Possibly Marketed Outside US
412
Investigational
186
US Approved Rx
157
US Previously Marketed
109
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Primary Target
Cyclooxygenase-2
14
Oxidative Stress
14
Farnesyl diphosphate synthase
10
GABA-A receptor; anion channel
10
GABA-B receptor
9
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Highest Phase
Approved
315
Not Provided
26
Phase III
23
Phase II
22
Phase I
12
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Approval Year
Unknown
1,458
1921
74
2024
23
2013
21
2016
21
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Condition
Unknown
119
Cancer
32
Type 2 diabetes mellitus
17
Pain
16
Breast cancer
15
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Treatment Modality
Primary
323
Preventing
88
Palliative
79
Diagnostic
76
Curative
44
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CNS Activity
CNS Active
98
CNS Penetrant
90
CNS Non-penetrant
62
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Originator
Guerbet
8
Chevreul, M.E.
7
Bayer
5
Pfizer
5
Burton, B.S.
4
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Substance Class
Chemical
1,738
Protein
119
Structurally Diverse
76
Mixture
74
Polymer
46
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GInAS Tag
KEW
7
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Code System
FDA UNII
2,058
CAS
1,868
PUBCHEM
1,711
EPA CompTox
1,524
MERCK INDEX
1,101
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Protein Type
ENZYME
21
RECEPTOR
13
PEPTIDE
4
CYTOKINE
3
REGULATOR PROTEIN
3
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ATC Level 1
VARIOUS
31
ALIMENTARY TRACT AND METABOLISM
27
MUSCULO-SKELETAL SYSTEM
23
DERMATOLOGICALS
21
CARDIOVASCULAR SYSTEM
19
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ATC Level 2
CONTRAST MEDIA
21
OPHTHALMOLOGICALS
11
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
10
DRUGS FOR TREATMENT OF BONE DISEASES
9
ANTIBACTERIALS FOR SYSTEMIC USE
8
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ATC Level 3
X-RAY CONTRAST MEDIA, IODINATED
16
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
9
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
9
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
6
OTHER ANTINEOPLASTIC AGENTS
6
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ATC Level 4
Bisphosphonates
8
Watersoluble, hepatotropic X-ray contrast media
8
Watersoluble, nephrotropic, high osmolar X-ray contrast media
7
Acid preparations
5
Paramagnetic contrast media
5
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Substance Form
Principal Form
1,763
Salts, Hydrates, Esters, etc.
295
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