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Showing 11 - 20 of 10,111 results

Status:
US Approved Rx (2004)
First approved in 2004

Class (Stereo):
CHEMICAL (ACHIRAL)



Trypan blue (trade name MembraneBlue, VisionBlue) is a vital stain used to selectively color dead tissues or cells blue. Live cells or tissues with intact cell membranes are not colored. Since cells are very selective in the compounds that pass throu...
Status:
US Approved Rx (2014)
First approved in 2003

Class (Stereo):
CHEMICAL (ACHIRAL)



Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. Ibandronate ...
Status:
US Approved Rx (2002)
First approved in 2001

Class (Stereo):
CHEMICAL (ACHIRAL)



Zoledronic acid (Reclast, Aclasta, Zometa) is an intravenous, highly potent amino-bisphosphonate approved worldwide, including in the USA, EU and Japan for use in patients with primary or secondary osteoporosis or low bone mass (approved indications ...
Status:
US Approved Rx (2018)
First approved in 2000

Class (Stereo):
CHEMICAL (EPIMERIC)

Targets:


Argatroban is a synthetic direct thrombin inhibitor derived from L-arginine. Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban does not require the co-factor antithrombin III for antithrombotic ac...
Status:
US Approved Rx (2018)
First approved in 1999

Class (Stereo):
CHEMICAL (ABSOLUTE)



Oseltamivir phosphate is an ethyl ester prodrug requiring ester hydrolysis for conversion to the active form, oseltamivir carboxylate. Oseltamivir carboxylate is an inhibitor of influenza virus neuraminidase affecting release of viral particles. Osel...
Status:
US Approved Rx (2007)
First approved in 1998

Class (Stereo):
CHEMICAL (ACHIRAL)



Risedronic acid is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism. The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral m...
Status:
US Approved Rx (2000)
First approved in 1997

Class (Stereo):
CHEMICAL (ACHIRAL)



Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Following topical application, tazarotene undergoes esterase hydrolysis to form its active metabolite, tazarotenic acid. When treating acne tazarotene may be taken in conjunct...
Status:
US Approved Rx (2022)
First approved in 1996

Class (Stereo):
CHEMICAL (ACHIRAL)



Sodium phenylbutyrate is a salt of an aromatic fatty acid. The compound is used to treat urea cycle disorders, because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen. Sodium phenylbutyrate is also...
Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...
Status:
US Approved Rx (2011)
First approved in 1995

Class (Stereo):
CHEMICAL (ABSOLUTE)



Latanoprost (free acid) is a metabolite of latanoprost which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester prodrug which is converted to the Latanoprost-acid by endogenous esterase enzymes. The free acid i...

Showing 11 - 20 of 10,111 results