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Search results for uridine root_names_stdName in Standardized Name (approximate match)

Showing 11 - 20 of 250 results

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TETRAHYDROURIDINE

0NIZ8H6OL8

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Status:

Investigational

Source:

NCT02664181: Phase 2 Interventional Active, not recruiting Lung Cancer

(2017)

Source URL:

https://clinicaltrials.gov/ct2/show/NCT02664181

Class (Stereo):

CHEMICAL (EPIMERIC)

Targets:

Cytidine deaminase

Conditions:

Non-small cell lung cancer

Sickle cell disease

Tetrahydrouridine is a potent competitive reversible inhibitor of cytidine deaminase. Tetrahydrouridine can inhibit cell proliferation by regulation of the cell cycle independent of cytidine deaminase (CDA) expression levels. Tetrahydrouridine may be useful for researching potential treatments for high CDA-expressing tumors. Tetrahydrouridine use, alone or in combination with the DNA methyltransferase inhibitor 5-fluoro-2’-deoxycytidine, is being evaluated in animal models and clinical trials for diseases, including cancer and mitochondrial DNA depletion syndrome.

CPZEN-45

LLP2Z9Z2EK

Search for Structure

Status:

Designated

Source:

FDA ORPHAN DRUG:783820

Source URL:

https://ginas.ncats.nih.gov/ginas/app/substance/LLP2Z9Z2EK

Class (Stereo):

CHEMICAL (ABSOLUTE)

UDP-Azido-GalNAc

7AC28DV2R4

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

1,2,4-BENZENETRIACETATE

903T7H7CP1

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

2′-O-Methyl-5′-uridylic acid

W676C2TW7P

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

2,3,5-tri-O-acetylribofuranose

X54595U4F2

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Tri-tert-butyl 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

89V3893HXD

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

5-Fluorodeoxyuridine triphosphate

FA9QF92ZKX

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

ALS-8144

UC4A9L46SG

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

VERALKAMINE N,O,O-TRIACETATE

371986TW0N

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Structure of TETRAHYDROURIDINE

EPIMERIC

TETRAHYDROURIDINE

Structure of CPZEN-45

ABSOLUTE

Structure of UDP-Azido-GalNAc

ABSOLUTE

UDP-Azido-GalNAc

Structure of 1,2,4-BENZENETRIACETATE

ACHIRAL

1,2,4-BENZENETRIACETATE

Structure of 2′-O-Methyl-5′-uridylic acid

ABSOLUTE

2′-O-Methyl-5′-uridylic acid

Structure of 2,3,5-tri-O-acetylribofuranose

ABSOLUTE

2,3,5-tri-O-acetylribofuranose

Structure of Tri-tert-butyl 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

RACEMIC

Tri-tert-butyl 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

Structure of 5-Fluorodeoxyuridine triphosphate

ABSOLUTE

5-Fluorodeoxyuridine triphosphate

Structure of ALS-8144

ABSOLUTE

Structure of VERALKAMINE N,O,O-TRIACETATE

ABSOLUTE

VERALKAMINE N,O,O-TRIACETATE

Showing 11 - 20 of 250 results

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