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Restrict the search for
ribavirin
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α-Ribavirin is an alpha-anomer of ribavirin, a broad spectrum antiviral nucleoside. It is unnatural minor impurity of ribavirin.
Status:
Investigational
Source:
NCT04387760: Phase 2 Interventional Completed SARS-CoV 2
(2020)
Source URL:
Class:
STRUCTURALLY DIVERSE
Status:
US Approved Rx
(2021)
Source:
ANDA215208
(2021)
Source URL:
First approved in 1999
Source:
NDA021087
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Oseltamivir phosphate is an ethyl ester prodrug requiring ester hydrolysis for conversion
to the active form, oseltamivir carboxylate. Oseltamivir carboxylate is an inhibitor of
influenza virus neuraminidase affecting release of viral particles. Oseltamivir is a well tolerated orally active neuraminidase inhibitor which significantly reduces the duration of symptomatic illness and hastens the return to normal levels of activity when initiated promptly in patients with naturally acquired influenza.