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Restrict the search for
itraconazole
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Status:
Other
Class (Stereo):
CHEMICAL (MIXED)
Targets:
Conditions:
Hydroxyitraconazole is the antifungally active metabolite of itraconazole formed in the liver by Ω-1-oxidation of itraconazole's 1-methylpropyl substituent. Hydroxyitraconazole has being shown to inhibit ATP-binding cassette yransporters P-Glycoprotein, BCRP, and BSEP..