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7-epidocetaxel (4-epidocetaxel) is an epimer of antitumor agent docetaxel (TAXOTERE). The presence of 7-epidocetaxel in docetaxel injection and in vivo epimerisation has been reported to be the cause for development of tumor resistance to chemotherapy including docetaxel by inducing tumor cell protein cytochrome P450 1B1.
