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Restrict the search for
chloramphenicol palmitate
to a specific field?
Status:
Investigational
Source:
NCT02561000: Phase 2 Interventional Completed Arterial Occlusive Diseases
(2016)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
PZ-128 (also known as P1pal7 ) is a cell-penetrating pepducin inhibitor of PAR1 that targets the receptor-G-protein interface on the inside surface of platelets. In preclinical studies, PZ-128 suppresses PAR1 aggregation and arterial thrombosis in guinea pigs and baboons and strongly synergized with oral clopidogrel. PZ-128 shows potent anti-metastatic and anti-angiogenic activity in Breast, Ovarian, and Lung Cancer preclinical studies. In clinical trials, PZ-128 shows a promising antiplatelet activity that provides rapid, specific, dose-dependent, and reversible inhibition of platelet protease-activated receptor-1 through a novel intracellular mechanism.
Status:
Investigational
Source:
NCT03748758: Phase 1 Interventional Completed Healthy Adult Volunteers
(2018)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ACHIRAL)
Dimetridazole is an anti-fungal and anti-protozoal drug traditionally used in veterinary for the prevention and treatment of histomoniasis in turkeys, genital trichomoniasis in cattle and hemorrhagic enteritis in pigs. Results from the in vitro and in vivo tests suggested, that dimetridazole was not genotoxic compound, but its use is legally limited, although this compound is still can be found in eggs.
Status:
Excipient
Source:
0.09%w/v INFILTRATION INJECTABLE, LIPOSOMAL
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
DIPALMITOYLPHOSPHATIDYLGLYCEROL (DPPG) is a phosphatidylglycerol in which the phosphatidyl acyl groups are both palmitoyl. DPPG is one of the commonly used lipids in liposome studies and biological systems research.
Status:
Designated
Source:
FDA ORPHAN DRUG:640618
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
