U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1911 - 1920 of 2002 results

Status:
US Previously Marketed
Source:
Bromauric Acid N. F.
(1921)
Source URL:
First marketed in 1921
Source:
Bromauric Acid N. F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Gold trichloride is used as a catalyst in synthesis of new compounds. It was shown that gold trichloride was not the marker of contact allergy and could not be recommended in patch testing.
Status:
US Previously Marketed
Source:
Bromauric Acid N. F.
(1921)
Source URL:
First marketed in 1921
Source:
Bromauric Acid N. F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Gold trichloride is used as a catalyst in synthesis of new compounds. It was shown that gold trichloride was not the marker of contact allergy and could not be recommended in patch testing.
Status:
US Previously Marketed
Source:
Bromauric Acid N. F.
(1921)
Source URL:
First marketed in 1921
Source:
Bromauric Acid N. F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Gold trichloride is used as a catalyst in synthesis of new compounds. It was shown that gold trichloride was not the marker of contact allergy and could not be recommended in patch testing.
Status:
US Previously Marketed
Source:
AM PLUS IMPROVED SODIUM MOLYBDATE by ROERIG
(1961)
Source URL:
First marketed in 1921
Source:
sodium molybdate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Molybdic acid refers to hydrated forms of molybdenum trioxide. There is no information related to the biological and pharmacological application of molybdic acid. It is known, that this substance is used as heterogeneous catalysts.
Status:
US Previously Marketed
Source:
Bromauric Acid N. F.
(1921)
Source URL:
First marketed in 1921
Source:
Bromauric Acid N. F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Gold trichloride is used as a catalyst in synthesis of new compounds. It was shown that gold trichloride was not the marker of contact allergy and could not be recommended in patch testing.
Elaidic acid is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid, which can be found in partially hydrogenated cooking oils. It was revealed, that elaidic acid inhibits HHT and HETE formation in human platelets incubated with arachidonic acid. Also was shown, that trans oleic acid increased plasma CETP activity, which increases low-density lipoprotein (LDL) cholesterol and decreases high-density lipoprotein (HDL).
Status:
US Previously Marketed
Source:
Sodium Bromide U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Bromide U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Hydrobromic acid is a useful reagent for generating organobromine compounds. It was shown that hydrobromic acid could initiate or exacerbate inflammatory pulmonary disease.
Status:
US Previously Marketed
Source:
Strontium Iodide U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Strontium Iodide U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Strontium ranelate is composed of an organic moiety (ranelic acid) and of two atoms of stable nonradioactive strontium. In vitro, strontium ranelate increases collagen and noncollagenic proteins synthesis by mature osteoblast enriched cells. The effects of strontium ranelate on bone formation were confirmed as strontium ranelate enhanced pre-osteoblastic cell replication. The stimulation by strontium ranelate of the replication of osteoprogenitor cell and collagen, as well as noncollagenic protein synthesis in osteoblasts, provides substantial evidence to categorize strontium ranelate as a bone-forming agent. In the isolated rat osteoclast assay, a pre-incubation of bone slices with strontium ranelate induced a dose- dependent inhibition of the bone resorbing activity of treated rat osteoclast. Strontium ranelate also dose-dependently inhibited, in a chicken bone marrow culture, the expression of both carbonic anhydrase II and the alpha-subunit of the vitronectin receptor. These effects showing that strontium ranelate significantly affects bone resorption due to a direct and/or matrix-mediated inhibition of osteoclast activity and also inhibits osteoclasts differentiation, are compatible with the profile of an anti-resorptive drug. Pharmacological and clinical studies suggest that strontium ranelate optimizes bone resorption and bone formation, resulting in increased bone mass, which may be of great value in the treatment of osteoporosis. Strontium ranelate is approved by EMA for the treatment of severe osteoporosis in postmenopausal women and in adult men.
Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neurodegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.
Potassium Glycyrrhetinate (CAS no. 85985-61-1) is the potassium salt of Glycyrrhetinic Acid. Potassium Glycyrrhetinate is also known as Olean-12-En-29-Oic Acid, 3-Hydroxy-1, 1-Oxo-, Monopotassium Salt. Potassium Glycyrrhetinate functions as a flavoring agent and skin-conditioning agent—miscellaneous in cosmetic products.

Showing 1911 - 1920 of 2002 results