O-Phthalaldehyde (OPA) is a chemical reagent that forms fluorescent conjugation products with primary amines. It is used for the detection of many biogenic amines, peptides, and proteins in nanogram quantities in body fluids. O-Phthalaldehyde is approved by FDA for use in test systems to detect blood urea nitrogen (BUN) for the diagnosis and treatment of certain renal and metabolic diseases. OPA is also a known desinfectant and has been approved for high-level sterilization of heat-sensitive medical instruments and is increasingly being used as a replacement in the healthcare industry for glutaraldehyde. OPA has also been approved for use as an indoor antimicrobial pesticide; an intermediate for the synthesis of pharmaceuticals, medicines, and other organic compounds.

P-nitrobiphenyl (PNB) is used as an intermediate for 4-aminobiphenyl. It was shown that PNB was a urinary bladder carcinogen in dogs. Reports of carcinogenicity in human do not exist, but 4-aminobiphenyl is a carcinogen for human, that is why the assumption exists that exposed in men to 4-aminobiphenyl may have been partially due to PNB. In addition, information exists that PNB has been studied in trials for the treatment of pelvic organ prolapse.

Dymanthine (Thelmesan) is an Anthelmintic, it is prepared as the hydrochloride and has some activity against hookworm infection, ascariasis, trichuriasis and hymenolepiasis. The drug appears to be safe, well tolerated and to cause few side effects (nausea, vomiting, headache, diarrhea, giddiness).