U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1581 - 1590 of 2238 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Mancozeb is a broad spectrum fungicide used in agriculture, professional turf management, and horticulture. Mancozeb is a member of the ethylene bisdithiocarbamate (EBDC) group of fungicides. Mancozeb itself is not fungicidal and can effectively be considered a profungicide which, when exposed to water, breaks down to release ethylene bisisothiocyanate sulfide (EBIS), which is then converted via the action of UV light into ethylene bisisothiocyanate (EBI). Both EBIS and EBI are believed to be the active toxicants and are thought to interfere with enzymes containing sulphydryl groups. This fatal disruption of core enzymatic processes is postulated to inhibit or interfere with at least six different biochemical processes within the fungal cell cytoplasm and mitochondria. Mancozeb should be regarded as a suspected developmental hazard and a presumed reproductive hazard in humans.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Showing 1581 - 1590 of 2238 results