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Details

Stereochemistry ACHIRAL
Molecular Formula C8H8O3
Molecular Weight 152.1473
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 3-HYDROXYBENZENEACETIC ACID

SMILES

OC(=O)CC1=CC=CC(O)=C1

InChI

InChIKey=FVMDYYGIDFPZAX-UHFFFAOYSA-N
InChI=1S/C8H8O3/c9-7-3-1-2-6(4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)

HIDE SMILES / InChI

Molecular Formula C8H8O3
Molecular Weight 152.1473
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Longitudinal urinary excretion of some "trace" acids in a human male.
1981 Feb 13
Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans.
1981 Jul
Plasma concentrations of p- and m-hydroxyphenylacetic acid and phenylacetic acid in humans: gas chromatographic--high-resolution mass spectrometric analysis.
1982 Jul 9
Metabolism of diafenthiuron by microsomal oxidation: procide activation and inactivation as mechanisms contributing to selectivity.
2001 Oct
Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands.
2005 Jul 1
Novel gamma-hydroxybutyric acid (GHB) analogs share some, but not all, of the behavioral effects of GHB and GABAB receptor agonists.
2005 Jun
Trace analysis of oxidized, nitrated, and chlorinated aromatic amino acids by capillary electrophoresis with electroosmotic flow modification allowing large-volume sample stacking.
2005 May
The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context.
2005 May 12
Kinetic mechanisms of the oxygenase from a two-component enzyme, p-hydroxyphenylacetate 3-hydroxylase from Acinetobacter baumannii.
2006 Jun 23
Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities.
2007 Mar
Phenylacetic acids were detected in the plasma and urine of rats administered with low-dose mulberry leaf extract.
2008 Aug
Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites.
2009 Feb 11
Bis(3-hydroxy-phenyl-acetato-κO,O')bis-(1H-imidazole-κN)nickel(II).
2009 Feb 28
Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells.
2009 Jul
Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus.
2009 Jun 19
Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans.
2009 May
Studies on the mechanism of p-hydroxyphenylacetate 3-hydroxylase from Pseudomonas aeruginosa: a system composed of a small flavin reductase and a large flavin-dependent oxygenase.
2010 Jan 19
Profiling of phenols in human fecal water after raspberry supplementation.
2010 Oct 13
Patents
Substance Class Chemical
Created
by admin
on Thu Jul 06 01:48:21 UTC 2023
Edited
by admin
on Thu Jul 06 01:48:21 UTC 2023
Record UNII
K59Z6Z8REF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3-HYDROXYBENZENEACETIC ACID
Systematic Name English
HMDB00440
Code English
M-HYDROXYPHENYLACETIC ACID
Systematic Name English
3'-HYDROXYPHENYLACETIC ACID
Common Name English
2-(3-HYDROXYPHENYL)ACETIC ACID
Systematic Name English
(3-HYDROXYPHENYL)ACETIC ACID
Systematic Name English
ACETIC ACID, (M-HYDROXYPHENYL)-
Common Name English
BENZENEACETIC ACID, 3-HYDROXY-
Common Name English
NSC-14360
Code English
3-HYDROXYPHENYLACETIC ACID
Systematic Name English
(M-HYDROXYPHENYL)ACETIC ACID
Systematic Name English
Code System Code Type Description
NSC
14360
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
CAS
621-37-4
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID90211148
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
PUBCHEM
12122
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
CHEBI
17445
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
FDA UNII
K59Z6Z8REF
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
ECHA (EC/EINECS)
210-684-4
Created by admin on Thu Jul 06 01:48:21 UTC 2023 , Edited by admin on Thu Jul 06 01:48:21 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> METABOLITE
PARENT -> METABOLITE
Excretion of 3-Hydroxyphenylacetic acid in the urine of human subjects (n=6, 0-24hr total) after rutin (176 micromoles) supplemented tomato juice; Unit: micromoles
IN-VIVO
URINE