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Search results for alpha root_notes_note in Note (approximate match)
The CYP3A subfamily catalyzes the formation of stereoisomer 6α-hydroxycortisol (6α-OHF) from cortisol. The metabolite is then excreted in the urine. Therefore, the urinary excretion ratio 6α-OHF/cortisol might be used as a non-invasive index for evaluating the in vivo CYP3A activity in humans.