Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H30O6 |
Molecular Weight | 378.4593 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])C[C@H](O)C4=CC(=O)CC[C@]34C
InChI
InChIKey=GNFTWPCIRXSCQF-HVIRSNARSA-N
InChI=1S/C21H30O6/c1-19-5-3-11(23)7-14(19)15(24)8-12-13-4-6-21(27,17(26)10-22)20(13,2)9-16(25)18(12)19/h7,12-13,15-16,18,22,24-25,27H,3-6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1
Molecular Formula | C21H30O6 |
Molecular Weight | 378.4593 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/22318698Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/10718654
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22318698
Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/10718654
The CYP3A subfamily catalyzes the formation of stereoisomer 6α-hydroxycortisol (6α-OHF) from cortisol. The metabolite is then excreted in the urine. Therefore, the urinary excretion ratio 6α-OHF/cortisol might be used as a non-invasive index for evaluating the in vivo CYP3A activity in humans.
Originator
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14367319
Curator's Comment: https://www.ncbi.nlm.nih.gov/pubmed/13894709
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:18:37 GMT 2023
by
admin
on
Sat Dec 16 05:18:37 GMT 2023
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Record UNII |
V55JM5DKO0
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Record Status |
Validated (UNII)
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Record Version |
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2242-98-0
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254633
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V55JM5DKO0
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DTXSID501316184
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admin on Sat Dec 16 05:18:37 GMT 2023 , Edited by admin on Sat Dec 16 05:18:37 GMT 2023
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