U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 141 - 150 of 602 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Antimycin A1b acts as a novel pesticide and fungicide as well is useful in antibiotics. Antimycin A1 is an inhibitor of ACL (ATP Citrate Lyase) against the substrate citrate with promising Ki value: 29.5 uM. ACL is aberrantly expressed in many immortalized cells and tumors, such as breast, liver, colon, lung and prostate cancers, and is correlated reversely with tumor stage and differentiation, serving as a negative prognostic marker. ACL inhibitors, such as Antimycin A1, offer a new insight into their potential application in cancer treatment.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Showing 141 - 150 of 602 results