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Restrict the search for
unoprostone isopropyl
to a specific field?
Status:
Investigational
Source:
NCT03074435: Phase 3 Interventional Completed Malaria
(2016)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Dimpylate (diazinon) is a nonsystemic organophosphate insecticide, an inhibitor of the enzyme acetylcholinesterase (AChE), which hydrolyzes the neurotransmitter acetylcholine (ACh) in cholinergic synapses and neuromuscular junctions. This results in abnormal accumulation of ACh in the nervous system. Dimpylate was first registered for use in the USA in 1956. It was developed as an insecticide, acaricide, and nematicide for use on a variety of pests for control of soil insects and pests of fruit, vegetables, and forage and field crops. It had been used extensively in home and garden applications, in formulations designed to prevent such pests as crickets or cockroaches from infesting homes or offices, and in pet collars. Due to the emerging health and ecological risks posed by diazinon, manufacturers agreed to phase out and cancel all residential products. Manufacturing of indoor use products containing dimpylatewas discontinued in 2001; manufacture of non-agricultural outdoor use products containing dimpylate was discontinued in 2003.
Status:
Class (Stereo):
CHEMICAL (ACHIRAL)
Probarbital is ethylisopropylbarbituric acid patented by Thorp, L as hypnotic and sedative agent.
Status:
Designated
Source:
FDA ORPHAN DRUG:922822
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Designated
Source:
FDA ORPHAN DRUG:618717
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Designated
Source:
FDA ORPHAN DRUG:230206
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Gossypol is a substance that is found in the cotton plant. It is removed from the seeds and used for medicine. Gossypol is effective as a nonhormonal male contraceptive; however, it has been documented to have irreversible effects on male fertility. Gossypol is reported to exhibit antioxidant, anticancer, antivirus, antiparasitic, and antimicrobial properties and lower plasma cholesterol. Nausea, emesis, anorexia, diarrhea, altered taste sensation, small intestine obstruction, and fatigue have been recorded in clinical trials as adverse reactions. Large amounts of gossypol can decrease potassium levels in the body. Low potassium levels can increase the side effects of digoxin.
![Structure of 2-[(4-Chloro-5-pyrimidinyl)oxy]-N-ethyl-5-fluoro-N-(1-methylethyl)benzamide](/img/703d23cb-9d37-495c-9b5d-071c9f8a2575.svg?size=200&context=fnmvoudgik)
![Structure of 2-{[(2,6-Difluorophenyl)methyl]isopropyl(oxycarbonylamino)}-4-[(dimethylamino)methyl]-5-[p-(3-methoxyureido)phenyl]-3-thenoic acid](/img/b69f6314-47e5-4636-9892-0720f2a43c33.svg?size=200&context=fnmvoudgik)
