U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 12201 - 12210 of 12523 results

Status:
Possibly Marketed Outside US
Source:
Whituben by OASIS TRADING
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

L-methylephedrine is an isomer of DL form, which possesses beta 1-adrenoceptor agonist activity, while d-isomer is suggested to have only low or no affinity for beta 1-adrenoceptors.
Status:
Possibly Marketed Outside US
Source:
ICE COLD ANALGESIC GEL
Source URL:
First approved in 2013
Source:
Gilchrist and Soames Moisturizing Lip Balm by ASP Global, LLc
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Brilliant Blue is an organic compound classified as a blue triarylmethane dye. It is coal tar derivative food dye; used as the di-NH4 or di-Na salts. Coloring agent. Brilliant Blue FCF, has been used in foods in the US since 1929. This color adds a distinctive, bright blue hue to beverages, beverage powders, dairy products, baked goods, dessert powders, confections, condiments, icings, syrups, jams, jellies, marmalades, liqueurs, extracts, dairy fats and oil, meat, seafood, snacks, dry mixes and seasonings, fruit preparations, convenient food, and flavors. Both the diammonium and disodium salts of FD&C Blue No. 1 are used. The disodium salt is used in foods, while the diammonium salt has limited usage in drugs and cosmetics.
Status:
Possibly Marketed Outside US
Source:
NCT00001521: Phase 4 Interventional Completed Congenital Adrenal Hyperplasia (CAH)
(1995)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Deslorelin is an GnRH agonist used in veterinary. It effects contraception by temporarily suppressing the reproductive endocrine system and preventing production of pituitary (FSH and LH) and gonadal hormones (estradiol and progesterone in females and testosterone in males). The observed effects are similar to those following ovariectomy or castration, but are reversed after the hormone content of the implant is depleted or the implant is removed. As an agonist, deslorelin first stimulates the reproductive system, which can result in estrus and ovulation in females or temporary enhancement of testosterone and semen production in males. Then, down-regulation follows the initial period of stimulation. Although deslorelin can also be an effective contraceptive in males of some species, manufacturer recommends its use primarily in females, since monitoring efficacy in females by suppression of estrous behavior or of gonadal steroids in feces is more straightforward than ensuring continued absence of sperm in males, since most institutions cannot perform regular semen collections. It can, however, be used to ameliorate aggression in males of some species, but higher dosages are usually needed. While the major application of deslorelin was initially male contraception, due to its two differing actions, either the stimulation of oestrus or the sterilization of fertility, its use has been increasing in the bitch as well. SUPRELORIN® F (deslorelin acetate) Implant is a once-yearly, subcutaneous implant that assists in the management of adrenal disease in ferrets.
Status:
Possibly Marketed Outside US
Source:
GMC Medical GF Advanced Derm Serum by Laboratoires dermo Cosmetik Inc
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Carcinine (beta-alanylhistamine) is a natural imidazole-containing peptide found in the non-protein fraction of mammalian tissues and possesses antioxidant and hydroxyl radical scavenging properties. Carcinine is also a selective histamine H3 antagonist.
Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin. The activity of tiamulin is largely confined to gram-positive micro-organisms and mycoplasma. Tiamulin acts by inhibiting protein synthesis at the ribosomal level. In veterinary medicine, tiamulin is used for treatment and prophylaxis of dysentery, pneumonia and mycoplasmal infections in pigs and poultry. Tiamulin is available as a 2, 10 or 20% premix for pigs and poultry, a 12.5% solution or 45% water soluble powder for addition to drinking water for pigs and poultry, or a 10% injectable formulation for pigs. Tiamulin inhibits protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

The cationic surfactant, stearamidoethyl diethylamine (SD) is an emulsifier used in topical medications and cosmetics. Stearamidoethyl Diethylamine is an ingredient found in a variety of cosmetics and personal care products, primarily in shampoos and other hair care formulas, as an emulsifier, anti-static agent, and hair conditioner. It has been reported to cause allergic contact dermatitis.

Showing 12201 - 12210 of 12523 results