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Restrict the search for
amphotericin b
to a specific field?
Status:
Investigational
Source:
Lipids Health Dis. Apr 2016;15:66.: Not Applicable Human clinical trial Completed Hyperlipoproteinemia Type II/enzymology
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Excipient
Source:
0.12mg ORAL TABLET
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Guinea green B is an organosulfur stain. It is used as a dye for silk and wool fabrics and as a biological stain.
Status:
Designated
Source:
FDA ORPHAN DRUG:898222
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
TGF-B-recpotor inhibitor (dihydropyrrolopyrazole, 13) is one of the series of optimized, bioavailable dihydropyrrolopyrazole TGF-beta receptor type I inhibitors synthesized at Ely Lilly and is an investigational antitumor agent.
Status:
Designated
Source:
FDA ORPHAN DRUG:904922
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Designated
Source:
FDA ORPHAN DRUG:803420
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Designated
Source:
FDA ORPHAN DRUG:795820
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Designated
Source:
FDA ORPHAN DRUG:877322
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Designated
Source:
FDA ORPHAN DRUG:800720
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Designated
Source:
EU-Orphan Drug:EU/3/18/2106
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Designated
Source:
FDA ORPHAN DRUG:166203
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 preferentially localizes in mitochondria and when exposed to 500- to 600-nm wavelength visible light delivered through the Theralux device, it becomes highly cytotoxic through oxidative damage. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential blood stem cells from healthy volunteers. TH9402 offers an excellent potential as an ex vivo photodynamic purging agent for autologous transplantation in multiple myeloma and breast cancer treatment. TH9402 photodynamic-cell-therapy process conditions recognized as safe for normal human haematopoietic stem cells and progenitors demonstrated the efficacy of the purging procedure on various leukaemias.
![Structure of 3-[[Ethyl-[4-[[4-[ethyl-[(3-sulfophenyl)methyl]amino]phenyl]-phenylmethylidene]cyclohexa-2,5-dien-1-ylidene]azaniumyl]methyl]benzenesulfonate](/img/5577232c-a245-4ddc-8fab-4ec7eb3793e5.svg?size=200&context=rboluvsvek)
![Structure of 4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol](/img/443d85c4-1262-4c6b-8f47-b20cf113f529.svg?size=200&context=rboluvsvek)
![Structure of 6-fluoro-9-methyl-9H-Pyrido[3,4-b]indole](/img/e8c1b749-0135-c93c-1d33-24d60b3f602f.svg?size=200&context=rboluvsvek)
