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Restrict the search for
telotristat ethyl
to a specific field?
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Verilopam is a potent analgesic.
Status:
Investigational
Class (Stereo):
CHEMICAL (UNKNOWN)
FENIMIDE, a succinimide derivative, is an antipsychotic drug. It is not found in any pharmaceutical preparations sold in the US. It was found that FENIMIDE produced a sedative effect prior to deeper central nervous system depression.
Status:
Investigational
Source:
INN:butoprozine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Butoprozine increased the action potential duration like amiodarone, depressed the plateau phase like verapamil and decreased the amplitude and the maximum rate of depolarization. Butoprozine injected intravenously depressed sino-atrial node function, lengthened A-V nodal conduction time and the A-V nodal refractory period, and prolonged the atrial refractory period. Thus butoprozine acted preferentially on parts of the myocardial tissue where the slow inward current seems to be particularly involved. In this respect, butoprozine was more active than amiodarone, but in contrast to this drug, butoprozine did neither prolong the ventricular monophasic action potential duration nor the ventricular refractory period.
Status:
Investigational
Source:
INN:betamethadol [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Betamethadol or β-methadol is an opioid analgesic under international control according to the UN Single Convention 1961. Betamethadol is an isomer of the racemic mixture of dimepheptanol.
Class (Stereo):
CHEMICAL (RACEMIC)
Tinisulpride is a sulfamoylbenzoic acid patented by Fabre, Pierre, S. A. as an antiemetic agent.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Ethonam is an antifungal compound. Its activity was evaluated in the treatment of chronic athlete's foot.
Status:
Investigational
Source:
NCT01120600: Phase 3 Interventional Completed Osteoporosis
(2010)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Odanacatib is a potent, selective, and neutral cathepsin K inhibitor, an enzyme involved in bone resorption. Merck & Co was developing odanacatib, a once-weekly, oral Odanacatib, for the treatment of postmenopausal osteoporosis and osteoporosis in men. Merck & Co. has discontinued development of its cathepsin K inhibitor odanacatib, citing an increased risk of cardiovascular events for the osteoporosis drug.
Class (Stereo):
CHEMICAL (ACHIRAL)
Bisaramil, an antiarrhythmic drug was developed as an inhibitor of calcium transport and as a membrane stabilizer. In addition, the drug showed tonic and frequency-dependent block that is most potent against the heart Na+ channel. However, the phase-II for Arrhythmias in Japan was discontinued.
Class (Stereo):
CHEMICAL (ACHIRAL)
Aloracetam [CAS 493] is a nootropic agent with potential in the treatment of Alzheimer's disease. Aloracetam was undergoing clinical evaluation with Hoechst for the treatment of Alzheimer's disease, but this research was discontinued later.
Status:
Investigational
Source:
INN:iminophenimide [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Iminophenimide is a piperazinedione derivative patented by American Cyanamid Co. as anticonvulsant.
