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Search results for pipobroman in Reference Text / Citation (approximate match)
Showing 1 - 1 of 1 results
Status:
US Previously Marketed
Source:
VERCYTE by ABBOTT
(1966)
Source URL:
First approved in 1966
Source:
VERCYTE by ABBOTT
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Pipobroman (trade names Vercite, Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. It is marketed by Abbott Laboratories. Pipobroman (PB) has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death
