U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 8941 - 8950 of 141793 results

Status:
Designated
Source:
FDA ORPHAN DRUG:112698
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

TAK-603 is a quinoline derivative, originally developed as a anti-rheumatic drug. TAK-603 selectively suppresses Th1 cytokine production. In animal models TAK-603 has the ability to suppress the immune system and protect cartilage from destruction. The development of TAK-603 has been discontinued.
Geneticin (G-418) is produced by Micromonospora phodorangea. The antibiotic has brad spectrum antibacterial activity similar to gentamicins and other previously described aminoglycosides but of particular interest because of its high activity against protozoa, amoebae, tapeworm and pinworm infections in mice. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 is commonly used in laboratory research to select genetically engineered cells.
Status:
Designated
Source:
FDA ORPHAN DRUG:326110
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Calcium benzoate is the calcium salt of benzoic acid. Used as a preservative, both antibacterial and antifungal. Calcium benzoate can be found in concentrated pineapple juice. People who suffer from asthma, aspirin sensitivity or the skin disease urticaria may have allergic reactions and/or find their symptoms become worse following consumption of benzoic acid, particularly in combination with tartrazine (E102). Calcium benzoate (E213) is approved for use as a food additive in the EU, USA and Australia and New Zealand.

Showing 8941 - 8950 of 141793 results