U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 2881 - 2890 of 141793 results

Status:
Investigational
Source:
INN:nafomine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nafomine is the muscle relaxant. It was tested on lower extremity spasms in spinal cord injuries.
Status:
Investigational
Source:
INN:nilestriol
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Nylestriol is a synthetic estrogen which is marketed in China under the brand name Wei Ni An. Nylestriol can be used as an effective and acceptable estrogen replacement therapy for postmenopausal women. It was found to be effective, safe and convenient in treating postmenopausal osteoporosis.
Status:
Investigational
Source:
INN:dropempine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dropempine (Abdoman) is ganglionic blocking agent. It is antihypertensive and anti-ulcerogenic drug. Dropempine has proved in the treatment of patients with uncomplicated duodenal ulcer. On the basis of its pronounced motility inhibiting effect on the gastrointestinal canal it may be additionally used for the treatment of diarrhoea. It is reported on 5 patients in which under Abdoman therapy a paralytic ileus developed as severe complication, so that it must be warned of an uncontrolled prescription of abdoman concerning this indication.
Status:
Investigational
Source:
INN:bipenamol [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Bipenamol is a benzenemethanol derivative used to prepare novel semicarbazide-derived inhibitors of human dipeptidyl peptidase I.
Status:
Investigational
Source:
INN:linotroban
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Linotroban is a potent and selective thromboxane (TXA2) receptor antagonist. It is known as a novel antithrombotic agent. Linotroban ingestion reduced significantly the thrombus volume. The coagulation, as measured by fibrin deposition and FPA plasma levels, was not significantly affected by Linotroban. It appears that the thromboxane A2 receptor antagonist linotroban reduces the thrombotic response by primarily impairing the platelet function at arterial blood flow conditions, and particularly at high wall shear rates. Linotroban had been in phase II clinical trial for the treatment of thrombosis. But this research was discontinued.
Status:
Investigational
Source:
INN:abrucomstat [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT04474470: Phase 1/Phase 2 Interventional Completed Solid Tumor, Adult
(2020)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT03214614: Phase 1 Interventional Completed Healthy
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:sonrotoclax [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:claficapavir [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Showing 2881 - 2890 of 141793 results