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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
XAV-939 was discovered as a selectively inhibitor of Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition, regulates axin levels and does not affect CRE, NF-κB or TGF-β. Wnt/b-catenin pathway has been implicated in many cancers.
![Structure of 4-Amino-6-[2-[5-[[4-chloro-6-(2-ethoxyethoxy)-1,3,5-triazin-2-yl]amino]-2-sulfophenyl]diazenyl]-3-[2-(2,5-disulfophenyl)diazenyl]-5-hydroxy-2,7-naphthalenedisulfonic acid](/img/0281a295-6784-4c7f-9835-d8adf333a553.svg?size=200&context=rtiyfafmos)
![Structure of 2-[5-Fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-[(1E)-2-phenyldiazenyl]-4,6-pyrimidinediamine](/img/0e10b94c-330c-432a-b79a-d4c88c991020.svg?size=200&context=rtiyfafmos)
![Structure of Hexahydro-5-hydroxy-4-[(triphenylmethoxy)methyl]-2H-cyclopenta[b]furan-2-one, (3aR,4S,5R,6aS)-](/img/d353e93c-e81c-4aa4-9704-f860befb1e4b.svg?size=200&context=rtiyfafmos)
