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Development Status
Other
107,652
Possibly Marketed Outside US
10,255
Investigational
9,777
US Approved Rx
1,612
US Previously Marketed
1,444
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Primary Target
DNA
153
Dopamine D2 receptor
145
Apoptosis
123
GABA-A receptor; anion channel
114
Serotonin 2a (5-HT2a) receptor
112
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Highest Phase
Approved
3,294
Phase II
697
Phase III
386
Phase I
309
Not Provided
289
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Approval Year
Unknown
120,729
2020
647
2012
523
2013
515
1921
496
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Condition
Unknown
1,477
Cancer
395
Pain
281
Hypertension
243
Breast cancer
229
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Treatment Modality
Primary
4,821
Curative
803
Palliative
644
Preventing
555
Diagnostic
324
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CNS Activity
CNS Active
1,896
CNS Penetrant
1,020
CNS Non-penetrant
429
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Originator
Pfizer
217
GlaxoSmithKline
119
Merck
116
Eli Lilly
110
Novartis
99
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Substance Class
Chemical
92,801
Structurally Diverse
26,880
Protein
6,376
Mixture
2,629
Polymer
2,375
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INN Stem
Chemical substance(-ine)
308
Monoclonal antibodies(-mab)
198
Tyrosine-kinase inhibitors(-tinib)
71
Peptides and glycopeptides(-tide)
70
Gene Therapy vectors(-vec)
66
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GInAS Tag
KEW
3,300
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
132,111
CAS
96,055
PUBCHEM
91,801
EPA CompTox
66,643
ECHA (EC/EINECS)
28,687
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Protein Type
MONOCLONAL ANTIBODY
878
PEPTIDE
668
ENZYME
483
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
115
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ATC Level 1
NERVOUS SYSTEM
455
ALIMENTARY TRACT AND METABOLISM
355
CARDIOVASCULAR SYSTEM
336
ANTIINFECTIVES FOR SYSTEMIC USE
334
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
319
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
207
ANTINEOPLASTIC AGENTS
196
OPHTHALMOLOGICALS
162
PSYCHOLEPTICS
156
CARDIAC THERAPY
104
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
129
DIRECT ACTING ANTIVIRALS
71
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
67
ANTITHROMBOTIC AGENTS
65
ANTIPSYCHOTICS
64
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ATC Level 4
Protein kinase inhibitors
44
Antibiotics
43
Other antineoplastic agents
42
Benzodiazepine derivatives
37
Enzymes
36
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Substance Form
Principal Form
132,111
Salts, Hydrates, Esters, etc.
18,037
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Substance Form
Principal Form
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3-Fluorocyclobutanamine, cis-
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C5P3VQT3J9
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
3-Fluorocyclobutanamine, trans-
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5X99FNC2UU
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
5-Hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
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F2SLJ5AX8X
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
2-TERT-BUTYL-1,3-DIOXANE
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8U3G4AF7L6
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
DPIA
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HNZ7L49KE6
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Other
Class (Stereo):
CHEMICAL (MIXED)
7-methyl(3'-O-methyl)GpppGP cap
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427EK6X4GY
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Status:
Other
Class (Stereo):
CHEMICAL (EPIMERIC)
2-[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetic acid, rel-
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CJ9Y5QQW2L
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Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
[(5S)-3-tert-Butyl-2-phenyl-1,3-oxazolidin-5-yl]methanol
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ZBN23C3M47
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Other
Class (Stereo):
CHEMICAL (EPIMERIC)
BA-1049, (R)-
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Y983WLP5LE
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
1-Methoxy-4-nitro-2-(2-propen-1-yloxy)benzene
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QC6N2E6LBD
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Class (Stereo):
CHEMICAL (ACHIRAL)
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