Showing 1 - 3 of 3 results
Class (Stereo):
CHEMICAL (ABSOLUTE)
Finasteride is a synthetic 4-azasteroid compound. This drug is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). Two distinct isozymes are ...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
3-Oxo-4-aza-5α-androstane-17β-(N-t-butylcarboxamide) (or dihydrofinasteride) is the reduced product of Finasteride. Finasteride acts as an alternate substrate for steroid 5α-reductase and is initially bound in an extremely stable enzyme-bound NADP-di...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
17β-Carboxyandrost-4-en-3-one is an intermediate in the synthesis of the drugs Dutasteride (D735000) and Finasteride. 17β-Carboxyandrost-4-en-3-one shows weak inhibition of Steroid 5-alpha-reductase and Androgen Receptor antagonism.