U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

FOSTRIECIN

MORE DETAILS

  ZO1648L551

Status:
Investigational
Source:
INN:fostriecin
Source URL:
https://tripod.nih.gov/npc/#Download
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Serine/threonine-protein phosphatase 4 catalytic subunit
2
DNA topoisomerase 2-alpha
2
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
6
Conditions:
Cancer
609
Fostriecin, an antitumor antibiotic produced by Streptomyces pulveraceus, is a strong inhibitor of serine/threonine protein phosphatases type 2A and type 4, and inhibits the catalytic activity of partially purified Topo II (type II topoisomerase) in a non-competitive manner.

FOSTRIECIN SODIUM

MORE DETAILS

  8TXS63IX8M

Status:
Investigational
Source:
INN:fostriecin
Source URL:
https://tripod.nih.gov/npc/#Download
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Serine/threonine-protein phosphatase 4 catalytic subunit
2
DNA topoisomerase 2-alpha
2
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
6
Conditions:
Cancer
609
Fostriecin, an antitumor antibiotic produced by Streptomyces pulveraceus, is a strong inhibitor of serine/threonine protein phosphatases type 2A and type 4, and inhibits the catalytic activity of partially purified Topo II (type II topoisomerase) in a non-competitive manner.
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966