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Serine/threonine-protein phosphatase 4 catalytic subunit

2

Histamine H1 receptor

315

Dopamine D2 receptor

297

DNA

278

Bacterial penicillin-binding protein

233

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Investigational

2

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Unknown

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Cancer

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Originator

Warner-Lambert|Parke Davis

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Chemical

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CHEBI

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FOSTRIECIN

ZO1648L551

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Serine/threonine-protein phosphatase 4 catalytic subunit

DNA topoisomerase 2-alpha

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Conditions:

Fostriecin, an antitumor antibiotic produced by Streptomyces pulveraceus, is a strong inhibitor of serine/threonine protein phosphatases type 2A and type 4, and inhibits the catalytic activity of partially purified Topo II (type II topoisomerase) in ...

a non-competitive manner.

FOSTRIECIN SODIUM

8TXS63IX8M

Export Data
Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Serine/threonine-protein phosphatase 4 catalytic subunit

DNA topoisomerase 2-alpha

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Conditions:

Fostriecin, an antitumor antibiotic produced by Streptomyces pulveraceus, is a strong inhibitor of serine/threonine protein phosphatases type 2A and type 4, and inhibits the catalytic activity of partially purified Topo II (type II topoisomerase) in ...

a non-competitive manner.

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