U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Investigational
Source:
INN:troquidazole [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Troquidazole (EGIS-4136) is a radiosensitizer. It is a nitroquinoline derivative which enhances the radiosensitivity of hamster’s ovarian cells in both normoxia and hypoxia. Misonidazole at a concentration of 5 mM exerted a radiosensitizing effect as strong as 0.5 mM EGIS-4136.